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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b05febad32f8c1d7d338992619711e8b366c389a644a69ab0be6adf33ea3c81e' 
  AND token = 'kMDsBrGNAEUZlxaD5HmmFqF8RXcnU4Nh31sz61/sVhs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}