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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e7e71a828b7b1980a01c4958242a3148daf9c1ae6481154f5571b467ea87ab4' 
  AND token = '1kndYaDy3O2wnQnombtY3h1LJRmnmKbfPNcPJs+N5fc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}