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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9466c27accd3869c8665ac5001b45831d2ff22ff31f3bb59e8930c48a63ffb08' 
  AND token = 'thvygJmIQMFv2m27tgIs7pjqWE8Hms5rWbixSTfj61M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}