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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c2cb2a8b2877fb4598e015b0e7d7e1de812b4c6c75d929c700391ea96e1c48c' 
  AND token = 'aPFwhwwoJA5aFbume6PELE5GigJ/Ti7bBWXlywnA+1k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}