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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b5e46146b31482b9ef0389e39dcf15538aacdab3a942c8868bb8e1c33d85d5da' 
  AND token = 'Iz/4NzNiJsS0Q9H1un+r0qxmX3fiAkOQJkSTujQzMJY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}