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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '771f4a3918e4cb739be42856898f977933e05c3bd0eef0475363e3b6ac9d019a' 
  AND token = 'HNhX3wZsi9UokfT52LvoYew5lI0FOMuV+Jva5X5BGzE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}