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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3cf74ed5cfc2078a27a21a379b1869e1fb47c52ca0b2176668d208980f81b7d5' 
  AND token = '1OhHWaom3TsNfU24hwwA81mNCtel39WgPJ3exXe1hEc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}