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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e51b81ad8c7c4b32a518ee4f6e69a370bdf2fc7bf529b92743a68e76d319a01a' 
  AND token = 'CUzs/IS105MN9ARLhYjao9C/hPllXY5lXeKN8p8/QUE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}