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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '89a2dddef626ec57623db8a36a9ad8849424b89b22bba76fbc2d6400d2deca8b' 
  AND token = 'cw6wRPnr67vXCmMWxJLfomVo41nRLFJr9x1dkxLOPcw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}