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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '41498d9d5a1b3bd8fae891069df29fca37cc9f6655b0ccc20ff13aa67c4af1b2' 
  AND token = 'HPeF/tBE9fChL7/Qa40ExSevNAAQsgANP2xAhuUtoYE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}