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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '69ba669ebaba0e46ee827a972321f04b25ad0781801eda6888feae0d72fcf450' 
  AND token = 'ECUqCveW7ps9aC+d1mw864OEIRtIC6Euo1boDLt4XIE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}