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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '918aaf29de24e2c7a147f2434e9f4818ac2af4f1699ad6f37925c51477c82be8' 
  AND token = 'O9bKRATRBT7j7CqbOcESSrzjdcgJqMIk4IFxh0SlXGc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}