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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e5de6a164fa86d223232c6f57072f02b61ee77e1df165a372d3d794b5398e1b8' 
  AND token = 'm32uJLhA6UP7IgbU2zgMEY0HMV6Ns9NGM/3ckneJ0wY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}