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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '29f1702f6289ac64eecb9881916238ef7b915e40f2fc6dac98912f0d5ab1f960' 
  AND token = 'lO6KgjpSC5jIoyZBVb2BeQa1WjBUG7aIQfMkA8jBRVo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}