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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5166a6e6cef50b2009159ad49d13a86511d7b824994f54e19688c8f866ab11a3' 
  AND token = 'A8/eZ96fuqqg+ZT2Kds6FbL1YRv7wEv8HHRCzdDeZOM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}