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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c3d7301f724315ac7a60dcc7a1eb2bfce8ad47a154f086a00090e9250d9a6541' 
  AND token = '03xuImG3RrgzvCwLGa9afKKIbL2KXis4baa1AEXTfuw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}