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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e147713be903ea67dec788a29c1e6273c2c3e6bb60c2aabc03460df894e14b0' 
  AND token = 'R3TQ1rnKbR6z4wOqeWN52x65+556HpLpux1XHL8gLYY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}