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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8589016874486d38de9401606269dfcac8a0fc1bed9a5e4d815aa82df8fa2906' 
  AND token = '+RwagWJhKsaBIFKlGiYF81knzrESoJNb+RIN4cEnjt8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}