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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c9294ca9a3964933a88309ea932ec148db77337c2dd43c3410dd9b517b03a72' 
  AND token = 'gfylb0VIdGmVwVpeHlY9awaLkP1DZhx5S3K8v5Ik3PQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}