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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '557b6f07866dd12dc7ec01817f6dd311eca828bbad202660d90334d46dec5246' 
  AND token = 'n42xWAt5XSsZG4LwydyrW1cIWKpoi0uXNr6Lz3/Qkzg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00067

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}