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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '859a48850b98ef0a5853d28fb6d9799d620379d577128ebd20ae3527afd9eff1' 
  AND token = 'wzvMnc8bw7f3nIYmbD3KYeSBuu3ysVaei5TN1HuJeo8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}