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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b9ae7e09d316e8c2d0d1c106fb22908704a1ab89de960d5eb5b77c60327d7b64' 
  AND token = 'UQJi+Uds9/3hvFl51HATLsrLw2kAAwRZ44fP0ELDi0w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}