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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd5a4646e67513abd78ab9282dec723923e4656ed7827de0f553941a3882214a1' 
  AND token = '6fBp31cFikV/4BaFAR2Uss08OwqGBKH1ZimTaiY6KxI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}