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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7e0f1f15c2dc27979a75b9671cd643ffe5cd8905607fab132964996d984c1db1' 
  AND token = 'YFQR7I3XWBWPVq1LmFpECbXOEf6jAwxWgrA4uj53M7s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}