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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9d0f66dcbdb913068144a7f9b238ca7a80f5d8bc5cb676d6472c93d7b036085e' 
  AND token = 'a9SxdYtLZklXr9+WtbYWDPKxAPbkMS8dlMGk4qYW1FI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}