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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45d3fab2986b08cabd186d1cb3241c7656e3dd6f24d64e5ba13539492740e70b' 
  AND token = 'dICAKTEse5TwpMJZTcQK86OtdNgqadh0Lkizyt739DY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}