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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '42c342053494d0f9973a033afbe8dde6cbdcc50f64a644fadcab1dd622352935' 
  AND token = 'PDXcaApAO8Tjuye8h67U47tw+iGS7rf3LGoDB3WbaCM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}