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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bc5cf16319e1e4d6b176e01b6c84089a5f6a870f524e91f575b4b90146654389' 
  AND token = 'vUmfVfSC4DhSDyELDBootws7op1sZcd2QJRc6uuupoU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}