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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '73a00825e53a34d67dc171f88a1b94b4eae47c9de0eb1528c6294022bad4465d' 
  AND token = 'DVgM5Ey3QRTntSfOO9PW0QOZEXI492djhxNub83D8qQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}