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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3c8a5fdb3f967a0bca924ca8c826fac78f4426ca3a2620fa39d0456186b25c44' 
  AND token = 's3yrOWbdc6CMai17buZkcsHvzC0JABnX6c0zyxkRxMo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}