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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c19a924b7115cde13a2ea29dafc99bb25e1b39e8350c9d084146ab2bbe43ea38' 
  AND token = 'e6CM0BY5hq/1TuRtu6kEB2FOsA1cmwfcX+OJo/8GJ5E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}