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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33199205847e5a18cda32594a3e552a60e201c62987211dafafeba2111505cba' 
  AND token = 'oF8KpfYroO3jmJxV7b587WqEpcQEEDK4f666DPdav38=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}