SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '322bc43e95edddff1ec6fc2ad237b7f237910901177b32eab7a5abe30d7dded5' 
  AND token = 'MV9cdQTLCto+VPVw19UyQc2/8NRSa3B5ByIG+hyP+vc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}