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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '61d331075d3246b24e949612847f7779d115434e21d2b4713e4e279358c8ee16' 
  AND token = 'EAfU8SWmhr6poW2D2prVYkib+pj/jYVAbSIkpxTWOUM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}