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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f720e2c7d55181b83ba8d64f543fc41bb064b6b07af24832274ca66bf5a11154' 
  AND token = 'k/1vkwEGpdKLCN/KBlmFGyvZWlMN50a5voKalc2UJbQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}