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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a05e458ce8af2e431619fa73ddd7179f84b38a195b9cd6433ca23d763ff0e433' 
  AND token = 'CzeQYr3dAU5UYzfKNyFS9d+27xEQyXcl819QIL8Yl5Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}