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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2dec9756865a9bc0b4d7e4d8ba3f7da4134ad709060187df0bfc6f802e47b7a8' 
  AND token = 'QRkdX0ZuNviTv+bwyoKD+S9jJt/2UgTuWlSdlu9juUc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}