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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '69b13e1f6e44b6fcde4750618bf677c395571613ac013901ca7b3af23f4d072e' 
  AND token = 'eEYF/MEiZyxOuCm+pVzSOxp4/083TKBPc8to8gT9mM4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}