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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22e1d42185f65918a83135cb7ea4c9b4fa875eb8c7d3b3a1d7e6433eb99da760' 
  AND token = '8jbMMgHNdcbqM+J9wG4NDq+43/js+ki4oO5/0PD3ZRo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}