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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f8ff6bdb294d3be7a452b9292c111a56b76c960f396c693e34b544d1a41e5e69' 
  AND token = 'UYE2nj4Aj4rwy7SQT/Jp6rgmrkNfvdHgZXtEhTsuTy0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}