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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '989f2e5a2b31ecd7901eb823d0d3daf6aa7fe5482340eddb8b9c715eee708408' 
  AND token = '3cFIFmFp9dCylZpbFOojLsh7Rw9dKExRfWgLFCugd4E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}