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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '12ef3f214c5fda83acb93b807d3e27f755b55892f53ee057f65562dacab745ce' 
  AND token = '2Mp5XxI/6F3/5pIEXUmW/+iScCAwo0WPJpCUho+Ffd8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}