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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '66d1cb41bb63ba142c0af8e2cf31fec94dd9061940dfa05ac6634b18f5735607' 
  AND token = 'IM4klkJ1RPku8U6HufGW2X24UtYHaBppCTrwcBA273s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}