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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aca92762bf29ca3926d9b72561baa656613ebc1d03fbe1b24752fbcdac10539b' 
  AND token = 'VS7oD2NdxtrDTISfOpJVWz1uVwDpYgR5ruGKnkN1+zE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}