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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7cbe7752eadaefd46af8da7bf29635b5262fa70714461ab5095181df00e2a1d0' 
  AND token = '6dQ1oCS3xfu0j2zVYHWrimcx4X3wmyZCMMhJEMYBBrw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}