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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '24ca64e1d92707a9e0950b9fa205e009da6939b36960a38a114a4dfc4e924b3c' 
  AND token = 'C5sCBEuP6oLTWe6Fmv/2NkV1ffBzie3NMUBvvUHwM94=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}