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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0d4146384644a2f792b9a1f8c3416fe31d871ea6f51c353e1ba843d211c818fc' 
  AND token = 'ZtW9ZQmP+sKoHDIiTUXnkWtxZqO2fKzgIiecS1/G78s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}