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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fd85ca99266381f222b0e233bb4c1997458596908c15202e14be4ee5354b40de' 
  AND token = '78ip6mVKBgh+ro9O6h3YjbBMbxWpocnuZK4FtbZf440=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}