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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d0d3ea5ebe6245be7ba65dcf522d791e6da36f0009cd91229f36eb8c6a98a74' 
  AND token = 'XAsbNUOv/vo7zy7wIhQqlI9S1EdqkODZkPku5/R7TmU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}