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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0a5aefb2e2508c34382ad72f684989ed9a10161cfb8a8521fa79a3d5a20808d4' 
  AND token = '9JiX/1VGRcbudMZ5DxT9nVeGH7nQ6i+7QMlqLPb4U4Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}